If you need to use a laser pointer in your presentation, your slides are too complicated.
if you have designed your slides well, then you should never need to use a pointer in your presentation. Each slide should intuitively guide your audience to the right part without having to show them with the aid of a pointing device. Keeping your slides simple and only having one element or point on each slide will guide your audience.
On occasions where you need to highlight a number or a word, you can always use a transition to change the colour of the number or word, or even use an animation to underline or circle the area you want highlighting.
Pointers are distracting and are a symptom of a greater problem with your slides. So if you feel you need to use a pointer, then go back and make your slides simpler. A pointer is never the solution.